Please use this identifier to cite or link to this item: http://er.nau.edu.ua:8080/handle/NAU/34057
Title: SEROLOGICAL AND BIOLOGICAL ACTIVITY OF LIPOPOLYSACCHARIDE FROM Escherichia coli L-19
Authors: Гаркава, Катерина Григорівна
Броварська, О.С.
Здоровенко, Е.Л.
Варбанець, Л.Д.
Keywords: Escherichia coli lipopolysaccharide
toxicity
pyrogenicity
mitogenic activity
Issue Date: 2015
Citation: Garkavaya K.G. Serological and biological activity of lipopolysaccharide from Escherichia coli l-19 / K.G. Garkavaya, L. D. Varbanets, E. L. Zdorovenko, O. S. Brovarskaya // Biotechnologia acta. -2015.- v. 8.- No 1. - p.32-38.
Abstract: The lipopolysaccharide from Escherichia coli L-19 was isolated, chemically identified and its nontoxicity but pyrogenicity were shown. The investigations of lipopolysaccharide influence on T- and B-lymphocytes indicate that it may be used as a mitogen in blasttransformation reactions since it is only in insignificant degree less active in comparison with the commercial one. It was shown that in reactions of Ouchterlony double immunodiffusion in agar LPS from E. coli L-19 exerts an activity of antigen in homological system. There were not established serological cross reactions between antiserum to heated E. coli L-19 cells and LPS from another of E. coli strain М-17 аnd also the representatives of Enterobacteriaceae species such as Budvicia aquatica, Rahnella aquatilis and Pragia fontium. These results indicate the absence of common antigenic determinants between the tested strains.
URI: http://er.nau.edu.ua:8080/handle/NAU/34057
Appears in Collections:Наукові праці співробітників кафедри біотехнології

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